This chapter presents an analysis of three representative cases of the evolution of e-commerce in China, with the objective of synthesizing the significant innovations and potential of this phenomenon within a specific historical context. These cases not only reflect the characteristics of the times but also demonstrate the practical application of the knowledge theory system in social practice. As an early pioneer in e-commerce, Suning.com offers consumers a comprehensive shopping experience through the integration of online and offline models. Tuniu Tourism employs big data technology to satisfy the increasing demand for tourism, thus exemplifying a company at the mature stage of development. The cross-border e-commerce platform based on Made-in-China.com optimizes product recommendations and services through user behavior analysis, thereby demonstrating innovative trends in the context of globalization. Each of these three types of enterprise reflects the diversity and dynamic changes of China’s e-commerce industry, and studying these cases is of great significance for promoting the development of e-commerce theory.