The multi-factor Bank security safe with alarm and access control system has been designed to modernize security in banking environments by integrating the most modern high authentication technologies. The use of RFID technological systems along with biometrics, like fingerprint or facial recognition, would provide great multi-factor authentication. The combination of access via a manual keypad would ensure that there is yet an open channel for cases of failure in RFID and biometric sensors. The system can provide an automatic security alarm alerting authorities to unauthorized entry and an emergency response mechanism to contact the authorities in cases of security lapses. This is envisioned to remedy the deficiencies in traditional banking security systems to provide comprehensive and believable solutions for balancing ease of access with an additional layer of security to protect critical financial infrastructures.