Extensive studies in ship tribology are prompted by biofouling. Since biofouling is a widespread problem, researchers have been hard at work developing antifouling technologies, such as biomimetic lubrication-pervaded surfaces as an alternative to superhydrophobic ones. In this work, authors utilized a vacuum impregnation apparatus to infuse perfluoropolyether oil into the permeable anode Zirconium Oxide (AZO) surfaces, resulting in the slippery liquid-infused Porous Surfaces (SLIPS). Oil was able to permeate the AZO pores due to the material’s strong capillary forces, resulting in a lubrication layer with minimal Contact Angle Hysteresis (CAH) and a persistently slippery surface. Phaeodactylum tricornutum was utilized for adhesive testing and decreased by 98.5% to the antifouling performance of Slippery Liquid-Infused Porosity (SLIPS). Microorganism biofilm formation efficiency was also studied. The findings demonstrated that the lubrication layer slowed the development of biofilm. The findings of this study are helpful for developing slippery liquid-infused porous surfaces and its antifouling system.