Effective surveillance and rapid response are critical to enhancing national security in modern defense operations. This paper presents the development and implementation of an Autonomous Defense System (ADS) using IoT and vision-based technologies to improve real-time threat detection and response capabilities. The ADS integrates multiple sensors, including thermal, standard, and night vision cameras, to provide a comprehensive view of the surroundings, enabling accurate threat identification. The system’s AI-driven software processes these data, allowing for rapid decision-making and sending immediate alerts to control rooms for fast response. Our test results demonstrate high accuracy in threat detection and reliable performance under various conditions, making this system a valuable tool for modern military operations.