This paper considered the influence of globalization processes on the life values of universities, provided the key definitions of the research, and characterized the process of transformation of traditional given the effect of the factors of the change of the university’s existence environment. The design and methodology of this research are based on an interdisciplinary approach, which allows combining the treatment and study of the key provisions of the paper from the position of philosophy, sociology, cultural studies, pedagogics, and institutionalism. Interpretation of the main definitions of this work from the position of the system approach allows considering internal processes of the transformation of the university’s traditional values under the influence of external values in the conditions of globalization. This paper presented the definition of the life values of universities, which were considered in the context of their reconsideration given the factors of the external environment, unified by the globalization processes of digitalization, sociocultural exchange, information expansion, etc. According to this, it was determined that universities rethink their mission and transform their life values, which allows them to better adapt to the changing paradigms of social values and to consolidate the social activity of the educational process’s participants. The main value of this paper lies in substantiating the value of universities for social development and the role of life values in understanding the place in society’s development by all participants of the educational process.