This chapter defines the critical role of nursing professionals in radiology and their contribution to safe, effective, and patient-centred care across various imaging procedures. It provides a comprehensive overview of nursing responsibilities before, during, and after radiological interventions such as CT scans with contrast, gastrointestinal studies, fluoroscopic procedures, mammography, biopsies, and chest X-rays. Special emphasis is placed on the unique position of radiology nurses in managing patient preparation, monitoring during procedures, emergency response during contrast reactions, and ensuring proper documentation. Additionally, the chapter highlights the importance of infection control and sterilization protocols, especially during mobile imaging like bedside radiography, and outlines how radiology nurses lead in implementing these safety measures. It also explains the educational and training needs of radiology nurses and how their clinical judgment and rapid response in acute situations can directly impact patient outcomes. Through detailed sections on workflow coordination, intravenous access, and interpreting imaging findings, this chapter aims to enhance understanding of nursing efficiency and interdisciplinary collaboration in diagnostic imaging settings. Overall, it presents a structured guide for nurses to improve clinical practices and uphold patient care standards in the field of radiology.