Scholarlink

This chapter examines intraoperative imaging techniques for margin assessment in breast-conserving surgery (BCS). Traditional methods like frozen section analysis and imprint cytology reduce reoperations (3.6–13.2%) but demand specialized pathology teams and time-intensive workflows. Intraoperative ultrasound lowers tumor-involved margins (3–4%) yet struggles with multifocal lesions and calcifications. Emerging NIR-II fluorescence imaging provides real-time, high-resolution visualization (up to 4 mm depth) without ionizing radiation, surpassing visible-light methods. However, its limited penetration compared to MRI/CT restricts deep-tissue use. Clinical trials underscore NIR-II’s potential as an adjunct tool, though fluorophore stability and targeted probe development remain challenges. Integrating NIR-II with conventional modalities may refine surgical precision, which reduces reoperations and healthcare costs. Advancements in hybrid imaging and contrast agents are pivotal for broader clinical adoption.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Advantages and Limitations vs. Other Medical Imaging Techniques

  • 章节

  • 发表日期：

    2025年

查看全文
  • Yong-Qu Zhang,
  • Zhao Wu

摘要

This chapter examines intraoperative imaging techniques for margin assessment in breast-conserving surgery (BCS). Traditional methods like frozen section analysis and imprint cytology reduce reoperations (3.6–13.2%) but demand specialized pathology teams and time-intensive workflows. Intraoperative ultrasound lowers tumor-involved margins (3–4%) yet struggles with multifocal lesions and calcifications. Emerging NIR-II fluorescence imaging provides real-time, high-resolution visualization (up to 4 mm depth) without ionizing radiation, surpassing visible-light methods. However, its limited penetration compared to MRI/CT restricts deep-tissue use. Clinical trials underscore NIR-II’s potential as an adjunct tool, though fluorophore stability and targeted probe development remain challenges. Integrating NIR-II with conventional modalities may refine surgical precision, which reduces reoperations and healthcare costs. Advancements in hybrid imaging and contrast agents are pivotal for broader clinical adoption.