Glaucoma is one of the major causes of blindness in the world that affects millions of people. Early detection and treatment are essential to prevent vision loss. This research introduces a novel hybrid model, namely 7L-DCNN-GBC, to classify the glaucoma severity stage. This model combines a 7-layer Deep Convolutional Neural Network (7L-DCNN) with a Gradient Boosting Classifier (GBC) where 7L-DCNN extracts the feature and GBC classifies the severity level. The regions’ YOLOv8-based instance segmentation is used for more accurate classification and localization. In this research, four datasets were considered for model performance evaluation; three benchmark datasets, namely REFUGE, ORIGA, and DRISHTI-GS) and one newly proposed dataset, namely AKMC, were gathered from a local hospital, Anwer Khan Modern Medical College Hospital (AKMMCH) in Dhaka, Bangladesh. The dataset contains 256 high-quality fundus images that were annotated by a retinal specialist team. The accuracy, precision, recall and specificity metrics are considered for model performance evaluation. The proposed dataset obtained the highest result with an accuracy, f1-score, precision, recall, roc, and specificity of 99.13%, 98.71%, 98.54%, 98.89%, 98.68%, and 98.79%, respectively. In addition, the YOLOv8-based instance segmentation model impressively identifies the region of interest with 98.71% mAP50 and 94.4% recall. The proposed model is notable for clinical application, aiding early glaucoma detection and personalized treatment strategies.

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A Hybrid DCNN-Gradient Boosting Approach for Glaucoma Severity Stage Detection with Instance Segmentation-Based Cup-Disc Localization

  • Romana Rahman Ema,
  • Pintu Chandra Shill

摘要

Glaucoma is one of the major causes of blindness in the world that affects millions of people. Early detection and treatment are essential to prevent vision loss. This research introduces a novel hybrid model, namely 7L-DCNN-GBC, to classify the glaucoma severity stage. This model combines a 7-layer Deep Convolutional Neural Network (7L-DCNN) with a Gradient Boosting Classifier (GBC) where 7L-DCNN extracts the feature and GBC classifies the severity level. The regions’ YOLOv8-based instance segmentation is used for more accurate classification and localization. In this research, four datasets were considered for model performance evaluation; three benchmark datasets, namely REFUGE, ORIGA, and DRISHTI-GS) and one newly proposed dataset, namely AKMC, were gathered from a local hospital, Anwer Khan Modern Medical College Hospital (AKMMCH) in Dhaka, Bangladesh. The dataset contains 256 high-quality fundus images that were annotated by a retinal specialist team. The accuracy, precision, recall and specificity metrics are considered for model performance evaluation. The proposed dataset obtained the highest result with an accuracy, f1-score, precision, recall, roc, and specificity of 99.13%, 98.71%, 98.54%, 98.89%, 98.68%, and 98.79%, respectively. In addition, the YOLOv8-based instance segmentation model impressively identifies the region of interest with 98.71% mAP50 and 94.4% recall. The proposed model is notable for clinical application, aiding early glaucoma detection and personalized treatment strategies.