Internal combustion engines (ICEs) are getting a lot of attention as the world shifts away from fossil fuels and towards renewable energy. Due to rising pollution and environmental concerns, the automotive industry is rapidly transitioning to sustainable fuels. Among the available fuels, hydrogen is an important one for industrial purposes. However, the successful usage of hydrogen in ICEs is dependent on a variety of injection techniques and fuel properties. The vaporization and atomization processes have a significant impact on the efficiency of hydrogen combustion. This study investigates hydrogen’s potential as both a primary and secondary fuel when combined with other fuels. It evaluates several induction methods, such as carburetion, port injection, and direct injection, to determine their capacity to capitalize on hydrogen’s high energy content while reducing pollutants, establishing hydrogen as a promising choice for cleaner transportation. The chapter also identifies technological issues related to hydrogen utilization in ICEs, such as injector design, fuel storage needs, pressure control systems, and distinctive combustion characteristics. However, hydrogen is categorized based on its fuel condition, with a focus on port fuel injection (PFI) and high-pressure direct-injection (HPDI) techniques, while addressing the operational issues of each methodology. Recent breakthroughs in injector technology, electronic controls, and hybrid configurations are also covered, with a focus on innovations that make hydrogen integration into ICEs easier. Finally, the environmental and economic repercussions of hydrogen as a fuel are compared to alternatives such as biofuels and battery electric vehicles, with an economic case study illustrating the feasibility of using hydrogen as a fuel source.