Fine-tuning is a promising technique for leveraging Transformer-based language models in downstream tasks. As model sizes continue to grow, updating all model parameters becomes increasingly costly. Parameter-efficient fine-tuning methods effectively address this issue by selectively updating a small subset of parameters. However, fine-tuning and most existing parameter-efficient fine-tuning methods require updating the same number of parameters as the initial size, ignoring the unequal contribution across Transformer blocks and leading to extremely inefficient allocation of computing resources. In this paper, we propose Progtuning, the novel fine-tuning framework combined with progressive learning for Transformer-based language models. Specifically, Progtuning progressively reduces the number of updated transformer blocks based on the contribution. Remarkably, Progtuning optimizes resource allocation and reduces the number of updated parameters by approximately 25%, while still maintaining competitive performance. And it also exhibits high adaptability with parameter-efficient fine-tuning methods, demonstrating excellent performance across various adaptation scenarios.