As the emerging development of the potential to transform the way that we teach and learn in the twenty-first-century education, the advancement of gamification has been a convincing partner to run in the process of education practices. Offering a close-tuning approach to engage with both learners and audiences, the efficiency of gamification would lead to enhance the transformative learning pathway. This chapter aims to examine the way of gamification with its features in enhancing the transformative learning in enabling the students’ acquisition of knowledge as a strategic achievement to obtain the twenty-first-century education. The finding revealed that the innovative concept of implementing the game scenario with the featured elements and principles could support the educational process and practices. This study will contribute to building an advanced scenario to further make the active transformative learning interaction with the unique characteristics of enjoyable and effective learning. With the profound target of goal, the strategic orientation of gamification could foster in leveraging the learning process and practices engaged with play and competition in order to give motivating support to the learners and thus would improve their learning outcomes. Through such integration of the elements like points, badges, and challenges into the learning process, the teaching process and practices require creating a more dynamic and engaging environment to cater to the diverse needs of students. From this point of view, the gamification played a role in advancing the academic performance, together with nurturing the essential skills like problem-solving and collaboration. With such a game-changer in education, the new way of inspiring the students could offer a transformation the traditional teaching methods into transformative-based instruction.