Nature-based solutions (NbS) are promising mitigation and adaptation measures that sustainably address societal and global problems, while simultaneously providing numerous benefits. However, its implementation is challenged by various issues such as financing, social acceptance, and governance concerns. This study aims to analyze how different drivers affect the successful implementation of NBS initiatives applying the Reporting Standards for Systematic Evidence Syntheses (ROSES) in environmental research. Results discuss the factors affecting NBS implementation from the themes based on the International Union for Conservation of Nature (IUCN) Global Standards for NbS including: (1) The NbS effectively addresses societal challenges, (2) The design of the NbS is informed by scale, (3) The NbS initiatives result in a net gain to biodiversity and ecosystem integrity, (4) NbS are economically viable, (5) NbS are based on inclusive, transparent, and empowering governance processes, (6) NbS equitably balance the trade-offs between achievement of primary goal(s) and the continued provision of multiple benefits, (7) NbS are managed adaptively, based on evidence, and (8) NbS are sustainable and mainstreamed within an appropriate jurisdictional context. Moreover, results found that NbS initiatives are challenged by low participation of stakeholders, limited funding opportunities, and supporting laws and policies. These findings provide recommendations including a participatory planning process, coordination between and among stakeholders, transparency and documentation, flexible operation and implementation, and establishment of monitoring and evaluation mechanisms. Overcoming these hurdles is essential to successfully implement NbS initiatives, maximize its benefits for the environment, economy, and society, and create a more resilient and sustainable urbanization.