The Global Risks Report, 2021 puts extreme weather, climate action failure, human environmental damage, biodiversity loss, and natural resource crises among the top ten risks by likelihood and impact (WEF, 2021). Over the recent years, Nature-based Solutions (NbS) have been increasingly recognized for their role in addressing varied socio-economic and ecological challenges, including the risks identified above. Despite the increasing recognition of NbS, the policy and decision-makers at the local level are not adequately equipped with analytical frameworks, tools and instruments to effectively understand and implement NbS which is most appropriate to their risk landscape and context. Further, they also face the challenge of a lack of adequate knowledge and tools for evaluating and scaling up the NbS. Against this backdrop, the chapter through an extensive literature review will study the existing policy landscape and associated institutional mechanisms including the frameworks and standards for better understanding, selection, implementation and integration of NbS. It will analyse how these instruments are helping the decision-makers and practitioners in undertaking risk-informed and evidence-based selection and uptake of NbS for their local contexts. Further, the chapter will bring forth cases highlighting the key barriers and enablers for mainstreaming NbS in DRM policies and practices.