Organic photovoltaics (OPVs) have emerged as potential and sustainable alternative photovoltaics (PV) technologies to silicon-based and p–n junction solar cells. OPV materials due to their unique features and advantages such as low cost, light weight, flexibility, semitransparent, cost-effective large area printability, high absorption coefficient, tunable optical band gap, and energy levels have attracted great attention as a promising green energy technology from academic and industrial community. Due to the intrinsic property of OPV materials, flexibility feature of organic solar cells (OSCs) makes these materials highly attractive for building integrated photovoltaics systems, automotive OPV, wearable electronics, organic light-emitting diode (OLED), organic field-effect transistor (OFET), electrochromic devices for buildings, automotive windows, and glazing applications. In this chapter an overview of the history, concepts and various applications of flexible OPV device from the material perspective and fabrication technology is presented. The recent developments in OPV materials, structure–property relation, design aspects of materials and solar cell architecture are summarized. The critical role of flexible electrodes in enhancing the functionality, adaptability, conductivity, transparency, sheet resistance, flexibility, durability, and chemical stability to make FOPV pave the way for their integration into diverse applications. Stability being the main bottleneck for commercializing OPVs various limiting factors for stability and the recent developments in strategies to overcome these have been presented. From device fabrication perspective recent progress made in design aspects, material choice, processing/printing technologies for efficient and inexpensive OPVs is discussed. Finally, future perspectives, existing challenges with potential strategies for viable commercialization of OPVs is highlighted.