A 58-year-old male patient with metastatic renal cell carcinoma presented with lethargy, confusion, anorexia, nausea, and constipation. He was polyuric and polydipsic over the past few days. He was found to be hypercalcemic. Hypercalcemia is mostly seen in solid tumors such as squamous cell carcinoma of the head, neck, and lungs, breast cancer, ovarian cancer, renal carcinoma, and some hematological malignancies, for example, leukemia, lymphoma, and multiple myeloma. A high index of suspicion is needed in patients with malignancy.