The need for new diagnostic tools, particularly rapid diagnostics for infectious diseases, arises from the increasing prevalence of highly drug-resistant gram-negative infections. These primarily include carbapenem-resistant Enterobacteriaceae, such as E. coli and Klebsiella, and carbapenem-resistant non-fermenting bacteria like Acinetobacter and Pseudomonas. The prevalence of these bacteria is rising in both community-acquired and hospital-acquired infections. Since the antibiotics used for these infections may differ, it is crucial to identify not only the bacteria but also the resistance mechanisms. This helps reduce the overuse of broad-spectrum antibiotics and allows for appropriate de-escalation of therapy if drug-resistant bacteria are not present.