In order to reveal the influence of cable wind ropes on the dynamic response and vibration coefficient of tower cranes under the excitation of wind, the theoretical equation for the vibration coefficient of tower cranes under the combined action of wind excitation and cable wind rope was firstly established. Secondly, simulate the pulsating wind speed by using the Davenport wind speed spectrum, and a finite element dynamic model of QTZ25 tower crane under the action of cable wind rope was constructed. The harmonic synthesis method was considered to obtain the wind excitation speed. Finally, the time history response of displacement at different nodes and the power spectral density curve of displacement at corresponding nodes of QTZ25 tower crane were obtained. Furthermore, the wind vibration coefficients at different nodes of the crane that vary with the height of the tower structure and the windward angle under wind excitation are obtained. It found that when the angle between the cable wind rope and the tower body is 45°, and the projected height of the cable wind rope on the tower body accounts for 50% of the total height of the tower body, the coefficient value of wind vibration decreases when the height is same. When the windward angle is 0, the maximum wind vibration coefficient value at different nodes of the tower body drops by 20.33%, and which drops by 19.80% when the windward angle is 45°. The results indicate that the cable wind rope can effectively reduce the dynamic characteristics, and the reasonable placement of cable wind ropes can achieve significant vibration reduction effects.