The operation of rail grinding vehicle is complex, involving theories of different disciplines such as dynamics, tribology, contact mechanics, hydraulics and control theory. To study the rail grinding process, a multi-software co-simulation model is established for the rail grinding vehicle is established in this paper. It includes four sub-models: dynamic sub-model of grinding trolley dynamics, rail-grinding wheel contact sub-model, hydraulic sub-model and control sub-model. The dynamic sub-model of grinding trolley can present the vertical displacement of grinding wheel, and the hydraulic system can present the contact pressure change according to the vertical displacement. According to the pressure change, the contact force and friction force between rail and grinding wheel are fed back to the dynamic sub-model to realize data circulation feedback. Finally, the dynamic parameters and hydraulic parameters are analyzed to verify that the model can reflect the real rail grinding process.