COVID-19 pandemic has challenged the fundamental existence of mankind. A microscopic virus posed the greatest question to mankind about its existence and the most evolved animal of the planet earth was flabbergasted. Zero preventive option, unidentified solution, high risk of infection, unexpected mortality have compelled the society hide behind the doors due to lockdown, work from home, and quarantine as a strategic step to escape the infection. Life and livelihood faced the greatest challenge of the century. On the one hand the death tolls were rising and the other was witnessing disastrous fall in commercial value. Due to easy access, scope of online purchase of medicine enhanced to a greater scale. Further, social media has progressively being used for sharing health information and for networking among clinician and patients. Such media played an important role on the adoption of online purchase of medicine. Objective of the current study is to reveal the factors influencing the online purchase of medicine during the pandemic and to analyse the impact of social media on purchase of medicine online. Randomly selected 200 respondents were approached for their opinion with the help of a structured questionnaire contains a set of close-ended questions. The opinions were coded on a five-point scale and were statistically analysed with the help of software. 3 factors emanated namely perceived objective value, perceived subjective value and perceived consultative value of online medicine purchase. The outcome of the study can be used as a game changing strategy for online medicine retails.