The issue of wellbore blockage in unconventional natural gas wells is escalating, significantly hampering the smooth and efficient production of gas wells. Initially, we delineated the common mechanisms underlying wellbore blockage during the developmental and production stages. Subsequently, we delved into the intricate specifics of wellbore blockage in gas wells across various unconventional reservoirs, considering both geological and engineering facets. Through an exhaustive analysis of diverse blockage causes, we conducted a comparative evaluation of the merits and demerits of different removal technology, while also projecting the future trajectory of gas wellbore blockage removal technology. Our findings elucidate several prevalent blockage mechanisms in gas wells, including scaling due to the high mineral content of formation water, corrosion of downhole tubulars, sand production, and hydrate blockage. Taking high-sulfur carbonate reservoirs as an illustration, wellbore blockage may also stem from sulfur deposition and acid residues caused by H2S. Similarly, in shale gas wells necessitating extensive hydraulic fracturing, wellbore blockage may result from the incompatible nature of complex fracturing materials, such as incomplete dissolution of bridging agents or temporary plugging agents. Furthermore, in offshore tight sandstone condensate gas reservoirs, condensate oil precipitation may exacerbate liquid accumulation in the wellbore. In response to these diverse wellbore blockage mechanisms, we delineate common countermeasures, including physical and chemical blockage removal techniques. It is imperative to perpetually scrutinize wellbore blockage mechanisms throughout the developmental and production phases and devise targeted blockage removal technology to facilitate the sustainable and efficient development of gas wells.