Mahu block of Xinjiang Oilfield is a tight conglomerate reservoir with high water injection pressure and poor water drive effect. Natural gas flooding technology is used to improve the development effect. However, the existence of fractures will cause premature gas channeling of oil wells. In order to cooperate with fracture sealing and channeling in such reservoirs to improve oil recovery, a slow expansion dispersion gel was developed in order to block the gas channeling channel in fracture sealing and channeling of fractured wells. Indoor optimization and evaluation of the dispersion system were carried out: the two positively and negatively charged dispersion particles can expand 15–25 times in 30 days, and the elastic modulus of the particles is higher than the viscosity modulus. After aging for up to 3 months, the two dispersions can maintain good water absorption morphology; Core experiments show that dispersed rubber particles can selectively block the main fractures, improve the oil extraction and displacement efficiency of fractured cores by more than 19%, and improve the oil displacement efficiency of matrix cores by more than 23%. The research results play an important supporting role in sealing channeling and EOR of fractured wells in Mahu tight reservoir.