Spatial-temporal cooperative guidance has great potential significance in both military and civil applications. Nevertheless, this topic has been confronting many open challenges, such as difficulties in precisely controlling the impact time, ensuring the guidance error convergence, simultaneously realizing the multiple impact constraints, and continuously satisfying the seeker’s FOV limit. In this context, this book provides several general yet practical solutions to improve the performance and application potential of the spatial-temporal cooperative guidance. The main research works and contributions of this book include the following aspects.