Significant public health challenges persist due to mosquito-borne diseases specially in tropical and subtropical regions like India. To control this, traditionally, nets, mosquito repellents, and insecticides are used which have limitations in terms of compliance, efficacy, and environmental impact. This study explores the potential for the development and transfer of a novel mosquito-repellent paint additive by Amity University Uttar Pradesh, having sustained and controlled mosquito-repellent properties which can be incorporated into any emulsion paint. The study follows a translational research framework aimed at bridging the gap between practical application and research. It emphasizes on development of product, identification of market needs, regulatory compliance, and collaborating with suitable companies for its commercialization. These strategic efforts have sparked the interest of leading players from the paint industry into this innovative technology. Compatibility studies established that the additive works well with emulsion paints, instigating additional validation and efficacy testing. The tests guided by adapted standards from Indian Council of Medical Research (ICMR), the American Society for Testing and Materials (ASTM), and World Health Organization (WHO) are essential to verify the product’s safety and effectiveness.