Light-Driven Micro/Nanomotors in Biomedical Applications
摘要
Micro/nanomotors are power devices that convert various forms of external energy into their own mechanical energy at the micro/nanoscale. Constructed with different structures and driven by various methods, micro/nanomotors execute movements such as propulsion, rotation, and aggregation. Based on this, micro/nanomotors exhibit specific functionalities under the influence of external fields, including electricity, magnetism, acoustics, and light. Among these, light-driven micro/nanomotors have unique advantages, such as non-contact operation, high flexibility, and high precision. Combined with optical gradient force propulsion, bubble propulsion, thermophoresis, electrophoresis, and diffusiophoresis, light-driven micro/nanomotors have progressively gained functionality in environmental management and micro/nano processing, with particular significance in biomedicine. They exhibit promising development potential and can serve as high-precision therapeutic tools for targeted drug delivery, thrombolysis, and photothermal therapy. Building upon the use of light-driven micro/nanomotors in biological and biomedical applications, this paper first provides a brief overview of their classification. Subsequently, it delves into their applications in cell manipulation, cargo delivery, photodynamic therapy, and photothermal therapy. Finally, it summarizes and provides prospects for the application of light-driven micromotors in the field of biomedicine.