Tarim Basin which located in northwest China, is rich in oil and gas resources, and Fuman Oilfield is the main oilfield for increasing oil and gas production, but the special engineering geological characteristics of this region bring a series of difficulties to drilling engineering. The special reservoir conditions of fracture and cave development carbonate reservoirs require the use of ultra-deep horizontal wells or high inclined wells for exploitation, which means long horizontal displacements between wellhead and target. It brings significant friction resistance when running BHA, also it is challenge to clean cuterings in the small gaps of annulus, thereby increasing the risk of stuck-pipe during drilling. The target formations are ultra-deep, with high hardness, high in-situ stress, and poor drillability. Additionally, the bottoming temperature is 170 ℃, which brings high requirements for the directional tools and drilling bits. This paper demonstrates the key technical difficulties and points of drilling ultra-deep horizontal wells in Fuman Oilfield by taking the Golle 3C well as an example. The optimisation of borehole trajectory through geo-engineering multidisciplinary ensured the safe and smooth running of BHA. Through the selection of drilling fluid system and optimisation of drilling parameters, the analysis of borehole cleanliness was completed to ensure the cleanliness and safety of the wellbore. The optimisation of directional drilling tools ensured the high efficiency of the drilling process. Finally, through remote real-time monitoring and analysis of the drilling data support, it guaranteed that the Guol 3C well was drilled to 9396 m and the 127 mm tailpipe was successfully lowered into place.