The reservoir in the study area has the characteristics of narrow, thin and strong heterogeneity. The sandstone on the whole has the characteristics of low density and low impedance, while mudstone has the characteristics of high density and high impedance (Cao G, Sui Y Study on the characteristics of polymer flooding in B reservoir of Lamadian oilfield. Petrochem Univ 33(3):31–36 (2020); Miall AD The geology of fluvial deposits: sedimentary facies, Basin analysis and petroleum geology. Berlin, Heidelberg, New York: Spring-Verlag, pp 57–98 (1996); He Y, Yu K Single channel identification and effect analysis of composite sand bodies in diverging plain. Pet Geo Oilfield Dev Daqing 24(2):17–19 (2005) [1–3]). However, the acoustic impedance overlap area of sand and mudstone is large, which is not conducive to thin reservoir prediction with seismic data. In view of the problems of thin sandstone thickness and difficult prediction, this paper based on the standardized processing of logging curves, realizes the effective prediction of the target layer well seismic combined with reservoir through the reconstruction of sand and mudstone sensitive curves and the optimization of key parameters of reservoir inversion constrained by geological model, and provides guarantee for the subsequent fine characterization of single sand body (Jin Z, Shi X, He M Identification method of single channel sand body. Xinjiang Pet Geol 31(6):572–575 (2010) [4]). In addition, “seismic trend guidance, well point microphase control” is used as the description method of well seismic combined with reservoir, giving full play to the prediction effect of multi-information fusion of well seismic on heterogeneous thin reservoir, and with the elevation difference, thickness difference, quality difference and thick-thin-thickness combination, the river channel is processed by stages, which greatly improves the characterization accuracy of single sand body distribution characteristics in the study area (Bai J Research on fine reservoir description technology based on well vibration. Northeast Petroleum University, (2012); Man W, Ma S Study on building structure of meander distributary channel sand body in Sazhong Oilfield, Daqing. Spec Oil Gas Reserv3(2):1–6 (2014) [5, 6]). Thus, the problem of prominent contradiction between reservoirs and planes is solved, and the demand of precise water injection for single sand body is met.