Acute fatty liver of pregnancy (AFLP) is a rare serious life-threatening complication of pregnancy that can lead to fulminant hepatic failure. It carries high risk of maternal and neonatal mortality if not diagnosed and treated promptly. Due to fatty infiltration of liver parenchyma, acute liver dysfunction occurs, which can precipitate coagulopathy, electrolyte imbalance, and multiorgan failure with an onset typically in late pregnancy.

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Acute Fatty Liver in Pregnancy

  • Samta Gupta,
  • Shivangini Sahay

摘要

Acute fatty liver of pregnancy (AFLP) is a rare serious life-threatening complication of pregnancy that can lead to fulminant hepatic failure. It carries high risk of maternal and neonatal mortality if not diagnosed and treated promptly. Due to fatty infiltration of liver parenchyma, acute liver dysfunction occurs, which can precipitate coagulopathy, electrolyte imbalance, and multiorgan failure with an onset typically in late pregnancy.