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Sphingolipids are found in all mammalian cell membranes and in plasma lipoproteins. They act as structural and functional (numerous biological/physiological functions) elements. The cornerstone of sphingolipids is long-chain sphingosine, which can be N-acylated by different fatty acids (mainly palmitoyl-CoA), leading to ceramide formation (Fig. 2.1).

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Overview of Gaucher Disease

  • 章节

  • 发表日期：

    2025年

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  • Saeedeh Saeedi,
  • Reihaneh Mohsenipour,
  • Parastoo Rostami

摘要

Sphingolipids are found in all mammalian cell membranes and in plasma lipoproteins. They act as structural and functional (numerous biological/physiological functions) elements. The cornerstone of sphingolipids is long-chain sphingosine, which can be N-acylated by different fatty acids (mainly palmitoyl-CoA), leading to ceramide formation (Fig. 2.1).