Hypervelocity weapons exhibit the characteristics of high striking accuracy and unique penetration behavior, which are out of the describing scope of existing impact theories. In this work, LS-DYNA code is used to simulate the hypervelocity penetration of earth penetrating projectile into rock. The penetration depth, velocity, acceleration, and cratering effect of projectile as well as the rock damage development are discussed. The prediction accuracies of numerical simulation are verified by the experimental results. Penetrating processes of large-scale projectile into rock at four different impact speeds are further simulated. The critical velocity of projectile is obtained and the maximum penetration depth of projectile in the erosion stage and the rigid stage is discussed, respectively. Prediction accuracies of maximum penetration depths and critical velocities using LS-DYNA code are finally verified by the robust A-T model and Forrestal model. It is found that the residual speed of large scale projectile penetration into high-strength rock is 527 m/s, and the size of upper crater and middle crater are about 2.17 and 1.21 times the projectile diameter respectively for striking speed up to 1500 m/s. Furthermore, radial crack occurs on the upper surface of the rock and the wing-shape damage in the middle extends along the crater. The critical striking velocity of earth penetrating projectile is 700 m/s. The relative error between numerical simulation and test data is 0.25~2.44% and 6.80% compared with theoretical results, indicating that the proposed numerical simulation offers an effective tool to evaluate projectile hypervelocity penetration into rock.