Air to air missiles needs time and space during the flight. Take missile attack the target as an example. When intercepting the target, the shorter the flight time of the missile, the shorter the reaction time left for the target; The larger the area of attack of the missile, the more capable it is of intercepting the target from danger. This article researches the four-dimensional spatiotemporal interceptable zone of air defense intercepting missiles, This research is carried out through a large number of missile interception-penetration simulation and missile and aircraft game confrontation flight analysis, by calculating some typical interceptable areas, the research results show that: Through the size of the interceptable zone of the same type of interceptor missiles is different, but the geometric space is similar; The four dimensional spatiotemporal interceptable zone of a missile, where the boundaries within the interceptable zone in the time domain are approximately equivalent, but the outer boundary will change with the speed of missile-target game; When the flight speed of the interceptor missile and the penetration target is very large, although the initial position of the two is far away, the flight time is very short,that is, the game flight time from the launch of the interceptor to the loss of the penetration target is very short, resulting in the interceptor not being able to intercept the penetration target, causing the penetration aircraft to collide with the interceptor and fly over.