This chapter presents a series of practical examples to illustrate potential real-world applications of the generalized topology optimizationTopology optimization approach discussed in this book. In particular, we focus on two distinct cases—one primarily driven by structural performanceStructuralperformance and the other mainly concerned with aestheticsAesthetics. The first case involves the design of a long-span steel–concrete composite bridgeBridge, while the second explores the creation of an innovative chairChair. These examples demonstrate that the concepts and techniques introduced in earlier chapters of this book can be employed to create designs that are both practically viable and aesthetically appealing.