Fe-based bulk amorphous alloy with low thermal conductivity was successfully prepared by doping Co65Cr15Zr10W10 alloy in Fe41Co7Cr15Mo14C15B6Y2 amorphous alloy. The thermal conductivity in the range of 25–150 ℃ and the electrical resistivity of Fe-based bulk amorphous alloy at room temperature were tested by laser flash thermal conductivity tester and four probe resistance tester respectively. The effect of the doping of Co65Cr15Zr10W10 amorphous alloy on the electrical resistivity and thermal conductivity, and the relationship between the temperature and the thermal conductivity were investigated, respectively. The results show that in the range of 25–150 ℃, the thermal conductivity of the Fe-based bulk amorphous alloy increases linearly with the increase of temperature. The thermal conductivity and the electrical resistivity of the Fe-based bulk amorphous alloy are decreased by doping Co65Cr15Zr10W10 alloy. When the doping content is higher than 10 at%, the thermal conductivity tends to be stable. Doping mainly results in the change of phonon thermal conductivity at room temperature, and the effect of doping on the electron thermal conductivity is very small. A formula for calculating the thermal conductivity of the Fe-based bulk amorphous alloy at room temperature is presented by using crystallization Tx, the relationship between phonon thermal conductivity and Tx is in linearity with Y = 0.06756X–37.31568, the relationship between total thermal conductivity and Tx is in linearity with Y = 0.06228X–30.58814.