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The leakage of cerebrospinal fluid (CSF) is a challenging condition and can result in significant medical complications. Conventional methods of testing, such as enzyme-linked immunosorbent assay (ELISA) and immunofixation electrophoresis, are available at limited clinical laboratories, adding to delays in accurate diagnosis and treatment. The work exhibited here is a device under development for the point-of-care detection of beta-2-transferrin (B2T), a biomarker exclusive to CSF that yields a sensitive and specific result within a few minutes, while simultaneously offering a measurable value.

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Emerging Techniques for the Rapid Detection of Cerebrospinal Fluid Leak

  • 会议论文

  • 发表日期：

    2025年

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  • Katyayanee Sharma,
  • Ajay Agarwal,
  • Amit Goyal

摘要

The leakage of cerebrospinal fluid (CSF) is a challenging condition and can result in significant medical complications. Conventional methods of testing, such as enzyme-linked immunosorbent assay (ELISA) and immunofixation electrophoresis, are available at limited clinical laboratories, adding to delays in accurate diagnosis and treatment. The work exhibited here is a device under development for the point-of-care detection of beta-2-transferrin (B2T), a biomarker exclusive to CSF that yields a sensitive and specific result within a few minutes, while simultaneously offering a measurable value.