There are different ways that NH-sulfoximines can be transformed, but the most common reaction position is on the N atom. A lot of them make N–C, N–S, and N–P bonds by using nucleophilic substitution reaction. Some reactions are also said to have occurred on the aryl groups that are connected to the S atom. Sulfoximines are capable of undergoing a wide range of transformations, which can result in the development of a wide variety of chemical entities with distinctive characteristics. The following is a list of common transformations that sulfoximines undergo: The process of reducing sulfoximines to their corresponding sulfides is known as reduction. This process typically involves the utilization of reducing agents such as hydrides or metal catalysts. Using more powerful oxidizing agents to oxidize sulfoximines results in the creation of sulfones. This process is referred as oxidation to sulfones.

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Transformation of Sulfoximines and Cyclic Sulfoximines

  • Qingle Zeng,
  • Alex Adonis Nking’wa

摘要

There are different ways that NH-sulfoximines can be transformed, but the most common reaction position is on the N atom. A lot of them make N–C, N–S, and N–P bonds by using nucleophilic substitution reaction. Some reactions are also said to have occurred on the aryl groups that are connected to the S atom. Sulfoximines are capable of undergoing a wide range of transformations, which can result in the development of a wide variety of chemical entities with distinctive characteristics. The following is a list of common transformations that sulfoximines undergo: The process of reducing sulfoximines to their corresponding sulfides is known as reduction. This process typically involves the utilization of reducing agents such as hydrides or metal catalysts. Using more powerful oxidizing agents to oxidize sulfoximines results in the creation of sulfones. This process is referred as oxidation to sulfones.