The proposed voice-controlled mouse system presents a novel contribution to the field of computer accessibility through its advanced integration of Speech-to-Text (STT), Text-to-Speech (TTS), and Natural Language Processing (NLP) technologies. This sophisticated combination enables the system to understand complex user commands, provide auditory feedback, and execute precise cursor movements, significantly enhancing usability compared to existing solutions. Tailored specifically for individuals with visual and mobility impairments, the system addresses unique user challenges by offering detailed audio descriptions and commands designed for non-visual navigation. Its high precision cursor control, achieved through advanced command parsing and cursor control algorithms, allows users to perform tasks requiring fine control. The comprehensive evaluation framework, which includes rigorous user testing, ensures practical effectiveness and user-centric refinements. Emphasizing the transformative potential of voice-controlled interfaces in fostering inclusivity, the paper advocates for widespread adoption, influencing future accessibility standards and tools. Designed with user-friendliness and modularity in mind, the system facilitates easy setup, customization, and extension, laying a robust foundation for future enhancements and continuous improvement in accessibility technology.