The Internet of Things (IoT) empowers the interconnection of various gadgets through networks, including shrewd gadgets, Radio Frequency Identification (RFID) labels, and sensors. Guaranteeing secure correspondence and admittance to delicate data among these gadgets is basic. Considering that a significant number of these gadgets have restricted assets like memory, size, speed, and power, utilizing super low-power utilization gadgets and lightweight cryptographic algorithms is fundamental. The memristor, an imaginative nanotechnology gadget, has become progressively liked in equipment security applications because of its unmistakable electrical reaction. Be that as it may, foreseeing the way of behaving of individual memristor gadgets represents a test for explicit numerical models. This study presents another Hardware Security Model (HSM) including memristive key age that depends basically on the one-of-a-kind way of behaving of the memristor's I-V qualities. The created memristor-based secret key has been used in the equipment execution of lightweight encryption conspire in view of the ANU-II block figure calculation. The dormancy for the memristive key age and ANU-II block figure is 16 and 13 clock cycles, individually. The proposed plan exhibits high throughput and effectiveness with low-power utilization of 0.053, 0.038, 0.339, 2.288, 3.422, and 0.241 watts when carried out on Austere 3, Simple 6, Virtex-4, Virtex-5, Virtex-6, and Virtex-7 FPGA stages, separately.