The present investigation aims at examining the mathematical model for the peristalsis-propagated Bingham model fluid with nanoparticles in an inclined conduit. The precise answers were then achieved by first transforming the governing two-dimensional equations showing the fluid flow into dimensionless equations. Approximations from the lubrication theory are employed. The expressions for temperature, concentration, velocity, average flux, pressure drop, coefficient of heat and mass transfer are estimated. Plots of streams are made versus relevant variables. Additionally, bolus dynamics were computed to describe peristaltic propulsion and streamline plots were created to highlight the trapping phenomena. This manuscript emphasizes on demonstrating the varied range of applications involving nanofluids, highlighting their enhanced controlled heat transfer capabilities. These nanofluids are ideal for these uses because of their special characteristics. Peristaltic micropumps and cutting-edge pharmacological engineering drug delivery devices are two applications of the study.