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In this study, we developed a fifth-order adaptive self-modelling network model to describe the association of paraquat in epigenetic pathways potentially leading to dopaminergic neuronal loss, one of the most important hallmarks of Parkinson’s disease (PD). This model is based on the structure and relevant biological processes in the animal and human brains.

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Higher-Order Adaptive Dynamical System Modeling for the Role of Environmental Neurotoxic Pesticide Paraquat on the Epigenetics of Neurodegeneration in N27 Dopaminergic Cells

  • 会议论文

  • 发表日期：

    2025年

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  • Bana Al Khayrat,
  • Jan Treur

摘要

In this study, we developed a fifth-order adaptive self-modelling network model to describe the association of paraquat in epigenetic pathways potentially leading to dopaminergic neuronal loss, one of the most important hallmarks of Parkinson’s disease (PD). This model is based on the structure and relevant biological processes in the animal and human brains.