David S. Ronderos, PhD, a biologist, in Evolution and the Integration of Knowledge, writes that the teaching of the subject of biological evolution presents unique challenges and opportunities. It is challenging not only because of the broad range of topics within biology, but also because of the wide array of philosophical and theological questions that necessarily arise when discussing the relationship between Creator and creation and the topic of human origins vis-à-vis the creation narratives contained in Sacred Scripture. These challenges, however, provide an opportunity for students to see how certain basic ideas from theology and philosophy can resolve apparent conflicts and thus demonstrate the harmony of faith and reason. Moreover, the topic of biological evolution readily lends itself to an in-depth exploration of the integration of knowledge and the unity of truth, as articulated in the writings of St. John Henry Newman and Pope St. John Paul II. The author reflects on a new course Evolution and the Integration of Knowledge offered at the University of Mary, North Dakota. This course aims to give an overview of the principles of evolution, which is the central organizing principle of biology, while also demonstrating how an appreciation for the various other fields of study, each with its own proper object and methods, its contributions and limitations, can lead to knowledge and wisdom.