As an emerging economic form, nighttime cultural and tourism consumption clusters have a significant impact on the development of the urban nighttime economy and the promotion of high-quality integration of the cultural and tourism industries. By utilizing methods such as the kernel density analysis and the geographical detector to comprehensively analyze the spatial distribution characteristics of three batches of national-level nighttime cultural and tourism consumption clusters, and delve into the influencing factors. The results indicate that: ① The distribution of national-level nighttime cultural and tourism consumption clusters at the provincial scale remains relatively concentrated, although the degree of concentration has decreased. ② In terms of spatial distribution structure, national-level nighttime cultural and tourism consumption clusters exhibit a spatial pattern of more clusters in the south than in the north, and more in the east than in the west. ③ Regarding spatial distribution density, national-level nighttime cultural and tourism consumption clusters show a “three main nuclei, multiple micro nuclei” spatial distribution pattern. The kernel density values of the traditional “three main nuclei” have all declined, more micro nuclei have begun to appear, and the spatial distribution of clusters is becoming more balanced. ④As for influencing factors, topography and climate are the core factors affecting the distribution of nighttime cultural and tourism consumption clusters, while resource endowment, lighting facilities, and tourism income are the main influencing factors.