Hexavalent chromium (Cr+6) is one of the major carcinogenic heavy metal present in the industrial wastewater. The purpose of this article is to find out the influences of various parameters on the elimination of Cr+6 ions from the waste water using activated sugarcane bagasse (SCB), neem saw dust (NSD), rice husk (RH) and neem leaf powder (NLP) as natural low cost adsorbent. It was found that the deletion of (Cr+6) ions is highly dependent on adsorbent amount, nature of adsorbent, solution strength, pH of the medium, shaking time and temperature. The results show that 90%-99% decrement of (Cr+6) ions may be possible using these natural adsorbents. The isotherm and kinetic studies of these adsorption process suggest that Langmuir isotherm and pseudo second order kinetics are leading model in this sorption process. The maximum adsorption capacity achieved for SCB, RH, SD and NLP were 12.85 mg/g, 13.51 mg/g, 41.06 mg/g and 76.34 mg/g respectively. It was found that these natural bio-adsorbents have excellent potential for elimination of carcinogenic metal ions from industrial waste water and may be a promising alternative and eco-friendly source of adsorbent.