Numerous Robotic Process Automation (RPA) market solutions with wildly disparate capabilities and business models are being put forth. RPA is still in its infancy, and its technology framework is continually evolving. There are very few comparative studies of RPA systems, and they do not make it simple to tailor the solution to the needs of the business choosing it. Thus, the research question is that it feasible to design a procedure that enables the choice of the most appropriate RPA tool while accounting for a particular business domain, reality, and set of requirements? In order to accomplish this, this study builds an artifact that comprises a collection of indicators to enable the long-term selection of the best RPA solution for each organization and/or business process using the methodological approach of Design Science Research. The artifact offers a methodology to categorize the level of adaptability of each solution for automating business processes, performs a comparative analysis of existing RPA solutions using a particular framework, and provides an overview of the features of currently available solutions on the market. The viability of the artifact is demonstrated using a real-world case situation. This test demonstrated the artifact’s capacity to meet the goals.