In terms of constructing healthy buildings and improving climate resilience, Nantong City, located in Jiangsu Province, China, presents several challenges and opportunities. Signs of surface faults associated with land subsidence have been noted in the city, suggesting the presence of geological challenges. Urban residential land use fragmentation has also been a problem in Nantong, leading to land waste and environmental degradation. In contrast, other cities in China, such as Changzhou and Yantai demonstrate different levels of resilience, indicating that Nantong has been assessed to have a modest level of resilience. To handle these challenges and improve climate resilience, it is crucial for Nantong to concentrate on aspects such as economic support capacity, social development capacity, endowment of natural resources, technology adaptation capacity, and risk management capacity. The importance of forward-thinking adaptation planning to improve the total adaptive capacity of the city system is vital, as is the government’s responsibility to lead the construction of climate-resilient cities. Essential measures include bolstering funding for urban climate change programs, enhancing city form and structure, and boosting Nantong’s resilience to climate change. A better understanding of the spatiotemporal features of urban development and an assessment of the effects of climate change on population urbanization can shed light on how to create resilience and achieve sustainable growth. Nantong could improve its climate resilience and address the challenges of climate change by using resilience assessment and planning models and methods. To construct healthy buildings and improve city resilience in the face of ongoing environmental and climate change, Nantong City could benefit from a holistic approach that incorporates geological considerations, urban development strategies, and rate evaluations.