A target-orientated seismic inversion workflow was developed to accurately characterize the fault-controlled fracture and cavity complex's spatial variation and reservoir distribution in Fuman Deep, Tarim Oilfield. This facies-controlled process involves a seismic sparse spike inversion to obtain a band-limited impedance volume, which is then subjected to a spatial trend filtering to obtain a background band-limited impedance volume independent of the fracture and cavity complexes. The two volumes are then subtracted to enhance the band-limited residual impedance of the fracture and cavity complexes. By combining this residual impedance volume with the low-frequency impedance trend of the limestone background, the absolute impedance of the fracture and cavity complex is obtained, and spatial porosity prediction is carried out with the well-log calibration. This workflow accomplishes quantitative characterization and accurate prediction of fault-controlled fracture and cavity complexes in Fuman Deep. The post-drilling and dynamic production data reserve analysis shows that the overall matches of reservoir prediction using this method have been significantly improved compared to the traditional methods. This method has been widely adopted in prospecting fracture and cavity complexes in deep karst carbonate reservoirs in the region.