The chapter addresses the work of the National Corn Commission in the distribution of improved seeds in the Mexican state of Jalisco in the middle of the last century. We analyze two moments in the existence of the institution. The first, between 1947 and 1952, was characterized by an emphasis on the political use of the seed and the extensive participation of rural teachers in the distribution of biotechnologies. In a second moment, between 1952 and 1962, the institution’s work focused on promoting agronomic research, experimentation, and tests in the fields of farmers who had good soils, irrigation, access to the urban market of Guadalajara, and political ties. In this second moment, the chapter problematizes the interpretations around the fact that only one-tenth of the Mexican corn surface was cultivated with improved seeds in 1960: from the reports of Reed Hertford or Nicolas Ardito Barletta to the recent studies of Jonathan Harwood. This study shows that those interpretations of the small-scale adoption of improved seeds in Jalisco hid a construction process of intensive corn agriculture. This agriculture explains the existence of a highly productive corn-growing area that exists to this day.