ICUBE-Q is a nanosatellite for Lunar remote sensing observation, which was launched into a large elliptical orbit around the moon by Chang ‘e-6. Its main purpose is to use its miniature camera to obtain detailed images of the lunar surface, and to carry out intelligent processing of image data in orbit and the verification of new technologies such as nanosatellite -based deep space lunar to Earth communication, so as to fully explore low-cost deep space exploration modes based on nanosatellite. The weighs of ICUBE-Q only 6.5 kg, is the first lunar exploration satellite under 10 kg in China, and the first deep space exploration satellite involved in domestic universities. This paper mainly introduces in detail the process of ICUBE-Q structure design according to the functional requirements, technical indicators and space environment requirements. Through the verification of vibration test, the rationality of the structure design is fully confirmed. The ICUBE-Q has been successfully launched into orbit this year, and has successfully completed various tasks in orbit according to the established plan. The structural design work of ICUBE-Q nanosatellite can provide a vital reference for the system design of nanosat deep space exploration mission.