Motivated by the desire to unify the physical realm with the biological realm, we first present the unified physical consequences of microcosmMicrocosm and macrocosmMacrocosm as applications of temporal toposTemporal topos, t-topos. That means that for the quantum realm, we must provide the formulations for the quantum dualityDuality, the quantum entanglementQuantum entanglement, the uncertainties, and the crucially important measurement problem. For the macrocosmMacrocosm, we give the notion of an ur-lightconeUr-lightcone corresponding to the notion of a light-cone in relativity. A formulation for the gravitational effectGravitational effect on the particle-wave dualityDuality phenomenon willWill be given.