To improve the water flooding efficiency in heterogeneous reservoirs, various profile control agents have been developed to plug the high-permeable layers. Though it could obviously expand the sweep volume, the oil washing efficiency of these agents still lack enhancing. In this paper, a novel EOR system named emulsion system of in-situ generating particles (EIGP) was constructed by oil-soluble phenolic resin, curing agent, and surfactant, which maintained liquid phase during injection process and could form solid particles automatically inside reservoir. This paper showed the construction process of the EIGP system, and the oil displacement and plugging ability and mechanism of EIGP were evaluated by IFT, contact angle measurements and core flooding experiments. The results showed that the EIGP system formed by LAS and SC had great properties on emulsion stability, reduce interfacial tension and alter wettability. The system could reach a maximum plugging ratio of more than 90%. Furthermore, the EIGP system could improve the oil recovery of 16.79% by increase oil washing effort. The profile control performance of the EIGP system was selective due to the pore compatibility, it tended to permeate more into high permeability cores with higher PR contents. Beside, its EOR mechanisms could be summarized into the synthesis effects of expanding sweep volume by plugging and enhancing oil washing effects by low IFT and wettability alteration. This work construct an in suit self-generated profile control system and establish a more systematic cognition on the application of the emulsion system of in-suit generating particles.