This chapter explores the application of design thinking principles to tackle the pressing issue of plastic waste management in India. With a focus on user-centric methodologies, the approach integrates empathy, creativity, and iterative prototyping to address the environmental challenges posed by plastic waste. By analyzing case studies and leveraging interdisciplinary research, the chapter highlights successful initiatives that reduce plastic pollution, enhance recycling processes, and promote sustainable practices. It emphasizes the need for collaborative efforts, aligning stakeholders from government, industry, academia, and civil society to foster innovation and effective waste management strategies. Through this holistic approach, design thinking not only addresses the technical aspects of waste management but also considers the socio-economic factors that influence waste practices across diverse Indian regions, contributing to the development of a resilient and sustainable waste management ecosystem.