As technology develops, medical devices like endoscopic systems have risen to the challenge of creating practical solutions that will decrease human suffering. Thus, research has focused on wireless capsule endoscopy (WCE). Two major obstacles for WCE systems, despite a lot of research, are the creation of smaller antennas and the path loss estimate. Consequently, we examined the path loss caused by biological tissue between the transmitting and receiving antennas in this research effort and proposed many miniaturized surfaces mount antennas with a capsule diameter of 12.23 mm. The proposed tiny, meandered kind of antenna for wireless capsules and planner antennas for path loss analysis are designed and simulated employing the finite integration technique (FIT). The Hugo body model is employed as the electromagnetic wave propagation medium for path loss analysis. 1.8 GHz is the frequency at which we have developed the suggested transmitter and receiver antenna. The suggested antenna's return loss, radiation pattern, and VSWR are also measured. The suggested antenna for a wireless capsule endoscopy system with a transmitting and receiving antenna showed a minimum loss of − 30 dB at 1.8 GHz, according to the analysis of path loss.